High-risk Minor Subclones are Important for Prognosis in Multiple Myeloma

Time: 12:25 pm
day: Day One Track A AM


  • Some HR abnormalities such as del17p, del1p32, or 1q gains are subclonal, and not detectable on bulk analysis
  • These subclones might be selected early during induction therapy
  • Single-cell analyses are mandatory to detect them at diagnosis to adapt treatment